以重组蛋白表达与纯化为基础
构建分子互作检测与功能验证平台

Hypericin photoactivation induces triple-negative breast cancer cells pyroptosis by targeting the ROS/CALR/Caspase-3/GSDME pathway.

Argonaute 2 inhibits RIG-I signaling via competition for viral RNA binding.

10.1016/j.isci.2025.113391

Concept of Targeted Drug Conjugate and Its Application in Reversing Drug Resistance.

10.1021/acs.jmedchem.4c03006

Targeting GRP75 with a Chlorpromazine Derivative Inhibits Endometrial Cancer Progression Through GRP75–IP3R-Ca2+-AMPK Axis.

Adv. Sci. 2024, 11, 2304203

RPS4XL encoded by lnc-Rps4l inhibits hypoxia-induced pyroptosis by binding HSC70 glycosylation site.

Received 18 July 2021; accepted 18 May 2022

Berberine modulates microglial polarization by activating TYROBP in Alzheimer’s disease.

Phytomedicine 135 (2024) 156237

SARS-CoV-2 envelope protein impairs airway epithelial barrier function and exacerbates airway inflammation via increased intracellular Cl− concentration.

Signal Transduction and Targeted Therapy (2024) 9:74

Malaria oocysts require circumsporozoite protein to evade mosquito immunity.

NATURE COMMUNICATIONS (2022) 13:3208

Identification and functional characterization of a novel BEL1-LIKE homeobox transcription factor GmBLH4 in soybean.

https://doi.org/10.1007/s11240-018-1419-4

Nanopore efficiently identifies hepatitis D virus antigens in vitro assay.

Materials Today Physics 46 (2024) 101479

Integration of genome wide association studies and co-expression networks reveal roles of PtoWRKY 42-PtoUGT76C1-1 in trans-zeatin metabolism and cytokinin sensitivity in poplar.

New Phytologist (2021) 231: 1462–1477, doi: 10.1111/nph.1746

Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis.

International Journal of Biological Sciences. Published: 2021.03.25, doi:10.7150/ijbs.56357

Discovery of Clinical Candidate (5-(3-(4-Chlorophenoxy)prop-1-yn-1-yl)-3-hydroxypicolinoyl)glycine, an Orally Bioavailable Prolyl Hydroxylase Inhibitor for the Treatment of Anemia.

2020, 63, 17, 10045–10060

Adenosine Monophosphate-Activated Protein Kinase (AMPK) Phosphorylation Is Required for 20-Hydroxyecdysone Regulates Ecdysis in Apolygus lucorum.

Int J Mol Sci. 2023 May 11;24(10):8587, doi: 10.3390/ijms24108587

The major-effect quantitative trait locus CsARN6.1 encodes an AAA ATPase domain-containing protein that is associated with waterlogging stress tolerance by promoting adventitious root formation.

2018 Mar;93(5):917-930, doi: 10.1111/tpj.13819. Epub 2018 Feb 2